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Development of Patient Education Material for Proton Pump Inhibitor Deprescribing: A Mixed-Methods Study.

Abstract : Background: Proton pump inhibitor (PPI) deprescribing is recommended in case of inappropriate use. Patient education materials are key elements in the deprescribing process. Objective: The study objective was to develop a patient education material for PPI deprescribing in primary care in France. Methods: Mixed methods study involving: i) a literature review of the existing patient education materials on PPI deprescribing to identify key points to optimize the layout and content of the document; ii) development of a first version of the brochure by a pluri-professional steering group following the national reference methodology of the French National Authority for Health (Haute Autorité de Santé) and iterative modifications of the patient brochure; iii) assessment of the content and understandability of the brochure by questionnaires followed by semi-structured interviews with target patients; and iv) iterative brochure readability assessment with the Flesh reading ease tool. Results: The final patient education material is a double-sided A3 brochure, i.e. four A4 pages. The first round of user testing by questionnaire (n=14 patients) led to modifications to improve the document understandability, validated in the second round of user testing by questionnaire (n=10 patients). The semi-structured interviews (n=10 patients) highlighted an adequate comprehension, whereas actionability required some minor modifications. The readability test score of the final education brochure was 59.4. Conclusion and relevance: This patient education brochure for PPI deprescribing is targeted to patients in primary care. Its impact on PPI deprescribing will be assessed in a population-based pragmatic trial in primary care.
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Contributor : Jean-Pascal Fournier Connect in order to contact the contributor
Submitted on : Monday, October 18, 2021 - 6:34:29 PM
Last modification on : Thursday, May 12, 2022 - 9:56:36 AM
Long-term archiving on: : Wednesday, January 19, 2022 - 9:51:29 PM


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Jérôme Nguyen-Soenen, Maud Jourdain, Jean-Pascal Fournier. Development of Patient Education Material for Proton Pump Inhibitor Deprescribing: A Mixed-Methods Study.. Annals of Pharmacotherapy, SAGE Publications, 2021, pp.10600280211046630. ⟨10.1177/10600280211046630⟩. ⟨hal-03384288⟩



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