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Sous-domaine niveau 1 : chim.ther

Proceedings of the 16th annual conference of the Groupement des Pharmacochimistes de l'Arc Atlantique (GP2A)

Jean Guillon , Guillaume Le Baut , Marc Le Borgne
16th GP2A, Sep 2007, Bordeaux, France. Journal of Enzyme Inhibition and Medicinal Chemistry, 23 (5), pp.587 - 587, 2008, Proceedings of the 16th annual conference of the Groupement des Pharmacochimistes de l'Arc Atlantique (GP2A), ⟨10.1080/14756360802204656⟩
N°spécial de revue/special issue hal-01689205v1
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Pro-Angiogenic Effects of Low Dose Ethoxidine in a Murine Model of Ischemic Hindlimb: Correlation between Ethoxidine Levels and Increased Activation of the Nitric Oxide Pathway

Nicolas Clere , Kim Hung Thien To , Samuel Legeay , Samuel Bertrand , Jean-Jacques Helesbeux , et al.
Molecules, 2017, 22 (4), pp.627. ⟨10.3390/molecules22040627⟩
Article dans une revue hal-02429803v1
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Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

Nicolas Lebouvier , Fabrice Pagniez , Young M Na , Da Shi , Patricia Pinson , et al.
Pharmaceuticals, 2020, 13 (8), 186 (32 p.). ⟨10.3390/ph13080186⟩
Article dans une revue hal-02913479v1

Doxycycline and its quaternary ammonium derivative for adjuvant therapies of chondrosarcoma

Imen Miladi , Magali Vivier , Marie-Mélanie Dauplat , Morgane Chatard , Sophie Besse , et al.
Cancer Chemotherapy and Pharmacology, 2017, 80 (3), pp.517 - 526. ⟨10.1007/s00280-017-3377-7⟩
Article dans une revue hal-01646771v1

Function-Oriented Synthesis toward Peloruside A Analogues

Anne-Caroline Chany , Frédéric Legros , Heloua Haroun , Uday Kumar Kundu , Bohdan Biletskyi , et al.
Organic Letters, 2019, 21 (9), pp.2988-2992. ⟨10.1021/acs.orglett.9b00413⟩
Article dans une revue hal-02087811v1

Antileishmanial activities and mechanisms of action of indole-based azoles

Fabrice Pagniez , Hiam Abdala-Valencia , Pascal Marchand , Marc Le Borgne , Guillaume Le Baut , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2006, 21 (3), pp.277 - 283. ⟨10.1080/14756360600700517⟩
Article dans une revue hal-01689215v1

Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors

Julien Defaux , Maud Antoine , Marc Le Borgne , Tilmann Schuster , Irene Seipelt , et al.
ChemMedChem, 2014, 9 (1), pp.217 - 232. ⟨10.1002/cmdc.201300384⟩
Article dans une revue istex hal-01683307v1

Design, Synthesis, and in vitro Antifungal Activity of 1-[(4-Substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

Rémi Guillon , Fabrice Pagniez , Francis Giraud , Damien Crépin , Carine Picot , et al.
ChemMedChem, 2011, 6 (5), pp.816 - 825. ⟨10.1002/cmdc.201000530⟩
Article dans une revue istex hal-01689176v1

Synthesis and Evaluation of Disubstituted N1- and N3-Imidazolidin-2-ones Acting as Potential Immunosuppressive Agents

Caroline Sabourin , Jean-Michel Robert , Sylvie Robert-Piessard , Delphine Carbonnelle , François Lang
Journal of Enzyme Inhibition and Medicinal Chemistry, 2008, 19 (6), pp.459-465. ⟨10.1080/14756360412331280482⟩
Article dans une revue hal-02389888v1

First Evidence That Oligopyridines, α-Helix Foldamers, Inhibit Mcl-1 and Sensitize Ovarian Carcinoma Cells to Bcl-x L -Targeting Strategies

Céline Gloaguen , Anne-Sophie Voisin-Chiret , Jana Sopkova-de Oliveira Santos , Jade Fogha , Fabien Gautier , et al.
Journal of Medicinal Chemistry, 2015, 58 (4), pp.1644-1668. ⟨10.1021/jm500672y⟩
Article dans une revue hal-02043913v1
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Lipid Composition, Fatty Acids and Sterols in the Seaweeds Ulva armoricana, and Solieria chordalis from Brittany (France): An Analysis from Nutritional, Chemotaxonomic, and Antiproliferative Activity Perspectives

Melha Kendel , Gaëtane Wielgosz-Collin , Samuel Bertrand , Christos Roussakis , Nathalie Bourgougnon , et al.
Marine drugs, 2015, 13 (9), pp.5606-5628. ⟨10.3390/md13095606⟩
Article dans une revue hal-01370285v1

A one-pot three-component synthesis of novel α-sulfamidophosphonates under ultrasound irradiation and catalyst-free conditions

Billel Belhani , Malika Berredjem , Marc Le Borgne , Zouhair Bouaziz , Jacques Lebreton , et al.
RSC Advances, 2015, 5 (49), pp.39324 - 39329. ⟨10.1039/C5RA03473F⟩
Article dans une revue hal-01694993v1

Design of new antifungal agents: synthesis and evaluation of 1-[(1H-indol-5-ylmethyl)amino]-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

Rémi Guillon , Francis Giraud , Cédric Logé , Marc Le Borgne , Carine Picot , et al.
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (20), pp.5833 - 5836. ⟨10.1016/j.bmcl.2009.08.089⟩
Article dans une revue istex hal-01689189v1

Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: Potent and selective aromatase inhibitors

Marie-Pierre Lézé , Marc Le Borgne , Patricia Pinson , Anja Palusczak , Muriel Duflos , et al.
Bioorganic and Medicinal Chemistry Letters, 2006, 16 (5), pp.1134 - 1137. ⟨10.1016/j.bmcl.2005.11.099⟩
Article dans une revue istex hal-01689230v1

Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells

Julien Defaux , Maud Antoine , Cédric Logé , Marc Le Borgne , Tilmann Schuster , et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (16), pp.3748 - 3752. ⟨10.1016/j.bmcl.2014.06.078⟩
Article dans une revue hal-01683305v1
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Marine Exopolysaccharide Complexed With Scandium Aimed as Theranostic Agents

Mattia Mazza , Cyrille Alliot , Corinne Sinquin , Sylvia Colliec-Jouault , Pascal E Reiller , et al.
Molecules, 2021, 2021-02-20, 26 (4), pp.1143. ⟨10.3390/molecules26041143⟩
Article dans une revue hal-03187695v1
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Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells

Appala Venkata Ramana Murthy , Vennu Narendar , Nangunoori Sampath Kumar , Pasula Aparna , Anagani Kanaka Durga Bhavani , et al.
European Journal of Medicinal Chemistry, 2019, 162, pp.334-347. ⟨10.1016/j.ejmech.2018.10.069⟩
Article dans une revue hal-01937242v1

Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors

Yvonnick Loidreau , Pascal Marchand , Carole Dubouilh-Benard , Marie-Renée Nourrisson , Muriel Duflos , et al.
European Journal of Medicinal Chemistry, 2012, 58, pp.171-183. ⟨10.1016/j.ejmech.2012.10.006⟩
Article dans une revue istex hal-02357785v1

Synthesis and molecular modelling studies of 8-arylpyrido[3',2':4,5thieno[3,2-d]pyrimidin-4-amines as multitarget Ser/Thr kinases inhibitors

Yvonnick Loidreau , Emmanuel Deau , Pascal Marchand , Marie-Renée Nourrisson , Cédric Logé , et al.
European Journal of Medicinal Chemistry, 2015, 92, pp.124-134. ⟨10.1016/j.ejmech.2014.12.038⟩
Article dans une revue hal-01135195v1

Three-dimensional model of cytochrome P450 human aromatase

Cédric Logé , Marc Le Borgne , Pascal Marchand , Jean-Michel Robert , Guillaume Le Baut , et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2005, 20 (6), pp.581 - 585. ⟨10.1080/14756360500220574⟩
Article dans une revue hal-01689233v1

Inhibition profiles of mono- and polyvalent FimH antagonists against 10 different Escherichia coli strains

T. Chalopin , Y. Brissonnet , Adeline Sivignon , D. Deniaud , L. Cremet , et al.
Organic & Biomolecular Chemistry, 2015, 13 (46), pp.11369 - 11375. ⟨10.1039/c5ob01581b⟩
Article dans une revue hal-01931394v1
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Secondary metabolites from lichen as potent inhibitors of advanced glycation end products and vasodilative agents

Andreas Schinkovitz , Pierre Le Pogam , Séverine Derbré , Emilie Vessieres , Patricia Blanchard , et al.
Fitoterapia, 2018, 131, pp.182-188. ⟨10.1016/j.fitote.2018.10.015⟩
Article dans une revue hal-01903310v1
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Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy

Romain Eychenne , Christelle Bouvry , Mickael Bourgeois , Pascal Loyer , Eric Benoist , et al.
Molecules, 2020, 25 (17), pp.4012. ⟨10.3390/molecules25174012⟩
Article dans une revue hal-02957763v1

New selective nonsteroidal aromatase inhibitors: Synthesis and inhibitory activity of 2,3 or 5-(α-azolylbenzyl)-1H-indoles

Marc Le Borgne , Pascal Marchand , Bénédicte Delevoye-Seiller , Jean-Michel Robert , Guillaume Le Baut , et al.
Bioorganic and Medicinal Chemistry Letters, 1999, 9 (3), pp.333 - 336. ⟨10.1016/S0960-894X(98)00737-9⟩
Article dans une revue istex hal-01689251v1

Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors

Marie-Pierre Lézé , Anja Palusczak , Rolf W Hartmann , Marc Le Borgne
Bioorganic and Medicinal Chemistry Letters, 2008, 18 (16), pp.4713 - 4715. ⟨10.1016/j.bmcl.2008.06.094⟩
Article dans une revue istex hal-01689195v1
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Targeting MHC Regulation Using Polycyclic Polyprenylated Acylphloroglucinols Isolated from Garcinia bancana

Chloé Coste , Nathalie Gérard , Chau-Phi Dinh , Antoine Bruguière , Caroline Rouger , et al.
Biomolecules, 2020, 10 (1266), pp.1-17. ⟨10.3390/biom10091266⟩
Article dans une revue hal-02930094v1
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Plastids of Marine Phytoplankton Produce Bioactive Pigments and Lipids

Parisa Heydarizadeh , Isabelle Poirier , Damien Loizeau , Lionel Ulmann , Virginie Mimouni , et al.
Marine drugs, 2013, 11 (9), pp.3425-3471. ⟨10.3390/md11093425⟩
Article dans une revue hal-02304112v1

Synthesis of a benzodioxinic analog of 8-methoxypsoralen

Thierry Besson , Nicolas Ruiz , Gérard Coudert , Gerald Guillaumet
Tetrahedron, 1995, 51 (11), pp.3197-3204. ⟨10.1016/0040-4020(95)00058-G⟩
Article dans une revue istex hal-02889857v1

Biophysical and structural characterization of mono/di-arylated lactosamine derivatives interaction with human galectin-3

Cédric Atmanene , Céline Ronin , Stéphane Téletchéa , François-Moana Gautier , Florence Djedaini-Pilard , et al.
Biochemical and Biophysical Research Communications, 2017, 489 (3), pp.281-286. ⟨10.1016/j.bbrc.2017.05.150⟩
Article dans une revue hal-02197010v1
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Preparative Isolation, Fast Centrifugal Partition Chromatography Purification and Biological Activity of Cajaflavanone from Derris ferruginea Stems

Sylvie Morel , Anne Landreau , van Hung Nguyen , Séverine Derbré , Philippe Grellier , et al.
Phytochemical Analysis, 2012, 23 (2), pp.152-158. ⟨10.1002/pca.1336⟩
Article dans une revue istex mnhn-02047397v1