Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors

Julien Defaux (1) , Maud Antoine (1) , Marc Le Borgne (1) , Tilmann Schuster (2) , Irene Seipelt (2) , Babette Aicher (2) , Michael Teifel (2) , Eckhard Günther (2) , Matthias Gerlach (2) , Pascal Marchand (1)

1 IICiMed - Cibles et Médicaments des Infections et de l'Immunité
2 Aeterna-Zentaris

Domaines: Chimie thérapeutique; Biologie cellulaire; Cancer; Sciences pharmaceutiques

Julien Defaux, Maud Antoine, Marc Le Borgne, Tilmann Schuster, Irene Seipelt, et al.. Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors. ChemMedChem, 2014, 9 (1), pp.217 - 232. ⟨10.1002/cmdc.201300384⟩. ⟨hal-01683307⟩